Life-course exposure to perfluoroalkyl substances and clinical markers of type 2 diabetes in early adulthood
نویسندگان
چکیده
منابع مشابه
Early-Life Exposure to Perfluoroalkyl Substances and Childhood Metabolic Function
BACKGROUND Perfluoroalkyl substances (PFASs) are synthetic chemicals that may persist in the environment and in humans. There is a possible association between early-life PFAS exposure and metabolic dysfunction in later life, but data are limited. METHODS We studied 665 mother-child pairs in Project Viva, a Boston, Massachusetts-area cohort recruited 1999-2002. We quantified concentrations of...
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OBJECTIVE Early developmental adaptations in response to undernutrition may play an essential role in susceptibility to type 2 diabetes, particularly for those experiencing a "mismatched rich nutritional environment" in later life. We examined the associations of exposure to the Chinese famine (1959-1961) during fetal life and childhood with the risk of hyperglycemia and type 2 diabetes in adul...
متن کاملPrenatal Exposure to Perfluoroalkyl Substances and Behavioral Development in Children
BACKGROUND In recent years, prevalence rates of behavioral disorders in children have increased. One factor possibly implied in the etiology of behavioral disorders is exposure to perfluoroalkyl substances (PFASs). The use of PFASs is highly integrated into everyday life, and exposure is ubiquitous. Exposure to PFASs during early life may be particularly harmful, as it represents a critical tim...
متن کاملPrenatal Exposure to Perfluoroalkyl Substances and Adiposity in Early and Mid-Childhood
BACKGROUND Few studies have examined whether prenatal exposure to perfluoroalkyl substances (PFASs) is associated with childhood adiposity. OBJECTIVE We examined associations of prenatal exposure to PFASs with adiposity in early and mid-childhood. METHODS We measured plasma PFAS concentrations in 1,645 pregnant women (median, 9.6 weeks gestation) enrolled in Project Viva, a prospective pre-...
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Background: According to the recent studies, vitamin D deficiency has been correlated with progress in type 2 Diabetes and Metabolic Syndrome. The aim of this study was to assess the effect of vitamin D supplementation on glucose and lipid profiles, blood pressure, and biomarkers of liver and kidney in type 2 diabetic patients. Methods: In this Double blinded randomized clinical t...
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ژورنال
عنوان ژورنال: Environmental Epidemiology
سال: 2019
ISSN: 2474-7882
DOI: 10.1097/01.ee9.0000609232.83646.6a